Adult hematopoietic stem cells require NKAP for maintenance and survival

Steady-state hematopoiesis is sustained through differentiation balanced with proliferation and self-renewal of hematopoietic stem cells (HSCs). Disruption of this balance can lead to hematopoietic failure, as hematopoietic differentiation without self-renewal leads to loss of the HSC pool. We find...

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Главные авторы: Pajerowski, Anthony G., Shapiro, Michael J., Gwin, Kimberly, Sundsbak, Rhianna, Nelson-Holte, Molly, Medina, Kay, Shapiro, Virginia Smith
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2010
Предметы:
Hematopoiesis and Stem Cells
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974581/
https://ncbi.nlm.nih.gov/pubmed/20610818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-268391
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