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NKAP Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors

NKAP is a multi-functional nuclear protein that has been shown to be essential for hematopoiesis. Deletion of NKAP in hematopoietic stem cells (HSCs) was previously found to result in rapid lethality and hematopoietic failure. NKAP deficient cells also exhibited diminished proliferation and increase...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Main Authors: Shapiro, Michael Jeremy, Anderson, Joshua, Lehrke, Michael Jonathan, Chen, Meibo, Nelson Holte, Molly, Shapiro, Virginia Smith
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783958/
https://ncbi.nlm.nih.gov/pubmed/31632967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00214
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