NKAP Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors

NKAP is a multi-functional nuclear protein that has been shown to be essential for hematopoiesis. Deletion of NKAP in hematopoietic stem cells (HSCs) was previously found to result in rapid lethality and hematopoietic failure. NKAP deficient cells also exhibited diminished proliferation and increase...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Shapiro, Michael Jeremy, Anderson, Joshua, Lehrke, Michael Jonathan, Chen, Meibo, Nelson Holte, Molly, Shapiro, Virginia Smith
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783958/
https://ncbi.nlm.nih.gov/pubmed/31632967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00214
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