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NKAP Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors

NKAP is a multi-functional nuclear protein that has been shown to be essential for hematopoiesis. Deletion of NKAP in hematopoietic stem cells (HSCs) was previously found to result in rapid lethality and hematopoietic failure. NKAP deficient cells also exhibited diminished proliferation and increase...

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Détails bibliographiques
Publié dans:Front Cell Dev Biol
Auteurs principaux: Shapiro, Michael Jeremy, Anderson, Joshua, Lehrke, Michael Jonathan, Chen, Meibo, Nelson Holte, Molly, Shapiro, Virginia Smith
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783958/
https://ncbi.nlm.nih.gov/pubmed/31632967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00214
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