Transcription factor Bcl11b sustains iNKT1 and iNKT2 cell programs, restricts iNKT17 cell program, and governs iNKT cell survival

Invariant natural killer T (iNKT) cells are innate-like T cells that recognize glycolipid antigens and play critical roles in regulation of immune responses. Based on expression of the transcription factors (TFs) Tbet, Plzf, and Rorγt, iNKT cells have been classified in effector subsets that emerge...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Uddin, Mohammad Nizam, Sultana, Dil Afroz, Lorentsen, Kyle J., Cho, Jonathan J., Kirst, Mariana E., Brantly, Mark L., Califano, Danielle, Sant'Angelo, Derek B., Avram, Dorina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941433/
https://ncbi.nlm.nih.gov/pubmed/27330109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521846113
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