Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells

PKD (protein kinase D) 2 is a serine/threonine kinase activated by diacylglycerol in response to engagement of antigen receptors in lymphocytes. To explore PKD2 regulation and function in TCR (T-cell antigen receptor) signal transduction we expressed TCR complexes with fixed affinity for self antige...

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Detalhes bibliográficos
Main Authors: Navarro, Maria N., Sinclair, Linda V., Feijoo-Carnero, Carmen, Clarke, Rosemary, Matthews, Sharon A., Cantrell, Doreen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462612/
https://ncbi.nlm.nih.gov/pubmed/22233340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111700
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