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Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells
PKD (protein kinase D) 2 is a serine/threonine kinase activated by diacylglycerol in response to engagement of antigen receptors in lymphocytes. To explore PKD2 regulation and function in TCR (T-cell antigen receptor) signal transduction we expressed TCR complexes with fixed affinity for self antige...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Portland Press Ltd.
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462612/ https://ncbi.nlm.nih.gov/pubmed/22233340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111700 |
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