Glucose represses dendritic cell-induced T cell responses

Glucose and glycolysis are important for the proinflammatory functions of many immune cells, and depletion of glucose in pathological microenvironments is associated with defective immune responses. Here we show a contrasting function for glucose in dendritic cells (DCs), as glucose represses the pr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lawless, Simon J., Kedia-Mehta, Nidhi, Walls, Jessica F., McGarrigle, Ryan, Convery, Orla, Sinclair, Linda V., Navarro, Maria N., Murray, James, Finlay, David K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459989/
https://ncbi.nlm.nih.gov/pubmed/28555668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15620
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