Vulnerability of the cysteine-less proton-coupled folate transporter (PCFT-SLC46A1) to mutational stress associated with the substituted cysteine accessibility method

Por Zhao, Rongbao, Shin, Daniel Sanghoon, Goldman, I. David
Publicado em 2011

Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1)

Por Zhao, Rongbao, Shin, Daniel Sanghoon, Fiser, Andras, Goldman, I. David
Publicado em 2012

Functional roles of the A335 and G338 residues of the proton-coupled folate transporter (PCFT-SLC46A1) mutated in hereditary folate malabsorption

Por Shin, Daniel Sanghoon, Zhao, Rongbao, Fiser, Andras, Goldman, David I.
Publicado em 2012

Role of the fourth transmembrane domain in proton-coupled folate transporter function as assessed by the substituted cysteine accessibility method

Por Shin, Daniel Sanghoon, Zhao, Rongbao, Fiser, Andras, Goldman, I. David
Publicado em 2013

Metastatic human epidermal growth factor 2 (HER2/neu) amplified breast cancer with acute fulminant hepatitis responding to trastuzumab, pertuzumab and carboplatin

Por Macias, Mariela N, Shin, Daniel Sanghoon, Ledezma, Blanca, Sadeghi, Saeed
Publicado em 2014

Membrane topological analysis of the proton-coupled folate transporter (PCFT-SLC46A1) by the substituted cysteine accessibility method

Por Zhao, Rongbao, Unal, Ersin Selcuk, Shin, Daniel Sanghoon, Goldman, I. David
Publicado em 2010

Human Epidermal Growth Factor Receptor 2 (HER-2/neu)-Directed Therapy for Rare Metastatic Epithelial Tumors with HER-2 Amplification

Por Shin, Daniel Sanghoon, Sherry, Timothy, Kallen, Michael E., Wong, Steven, Drakaki, Alexandra
Publicado no Case Rep Oncol (2016)

A P425R mutation of the proton-coupled folate transporter causing hereditary folate malabsorption produces a highly selective alteration in folate binding

Por Shin, Daniel Sanghoon, Zhao, Rongbao, Yap, Enghui H., Fiser, Andras, Goldman, I. David
Publicado em 2012

Random Mutagenesis of the Proton-coupled Folate Transporter (SLC46A1), Clustering of Mutations, and the Bases for Associated Losses of Function

Por Zhao, Rongbao, Shin, Daniel Sanghoon, Diop-Bove, Ndeye, Ovits, Channa Gila, Goldman, I. David
Publicado em 2011

Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation

Por Aluri, Srinivas, Zhao, Rongbao, Lin, Kai, Shin, Daniel Sanghoon, Fiser, Andras, Goldman, I. David
Publicado no J Biol Chem (2019)

Functional roles of aspartate residues of the proton-coupled folate transporter (PCFT-SLC46A1); a D156Y mutation causing hereditary folate malabsorption

Por Shin, Daniel Sanghoon, Min, Sang Hee, Russell, Laura, Zhao, Rongbao, Fiser, Andras, Goldman, I. David
Publicado em 2010

Identification of novel mutations in the proton-coupled folate transporter (PCFT-SLC46A1) associated with hereditary folate malabsorption

Por Shin, Daniel Sanghoon, Mahadeo, Kris, Min, Sang Hee, Diop-Bove, Ndeye, Clayton, Peter, Zhao, Rongbao, Goldman, I. David
Publicado em 2011

Global alteration of T-lymphocyte metabolism by PD-L1 checkpoint involves a block of de novo nucleoside phosphate synthesis

Por Palaskas, Nicolaos Jay, Garcia, Jacob David, Shirazi, Roksana, Shin, Daniel Sanghoon, Puig-Saus, Cristina, Braas, Daniel, Ribas, Antoni, Graeber, Thomas Glen
Publicado no Cell Discov (2019)

Repurposing metformin for cancer treatment: current clinical studies

Por Chae, Young Kwang, Arya, Ayush, Malecek, Mary-Kate, Shin, Daniel Sanghoon, Carneiro, Benedito, Chandra, Sunandana, Kaplan, Jason, Kalyan, Aparna, Altman, Jessica K., Platanias, Leonidas, Giles, Francis
Publicado no Oncotarget (2016)

PD-1 blockade expands intratumoral T memory cells

Por Ribas, Antoni, Shin, Daniel Sanghoon, Zaretsky, Jesse, Frederiksen, Juliet, Cornish, Andrew, Avramis, Earl, Seja, Elizabeth, Kivork, Christine, Siebert, Janet, Kaplan-Lefko, Paula, Wang, Xiaoyan, Chmielowski, Bartosz, Glaspy, John A., Tumeh, Paul C., Chodon, Thinle, Pe’er, Dana, Comin-Anduix, Begoña
Publicado no Cancer Immunol Res (2016)

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

Por Garcia-Diaz, Angel, Shin, Daniel Sanghoon, Moreno, Blanca Homet, Saco, Justin, Escuin-Ordinas, Helena, Rodriguez, Gabriel Abril, Zaretsky, Jesse M., Sun, Lu, Hugo, Willy, Wang, Xiaoyan, Parisi, Giulia, Saus, Cristina Puig, Torrejon, Davis Y., Graeber, Thomas G., Comin-Anduix, Begonya, Hu-Lieskovan, Siwen, Damoiseaux, Robert, Lo, Roger S., Ribas, Antoni
Publicado no Cell Rep (2017)

Primary resistance to PD-1 blockade mediated by JAK1/2 mutations

Por Shin, Daniel Sanghoon, Zaretsky, Jesse M., Escuin-Ordinas, Helena, Garcia-Diaz, Angel, Hu-Lieskovan, Siwen, Kalbasi, Anusha, Grasso, Catherine S., Hugo, Willy, Sandoval, Salemiz, Torrejon, Davis Y., Palaskas, Nicolaos, Rodriguez, Gabriel Abril, Parisi, Giulia, Azhdam, Ariel, Chmielowski, Bartosz, Cherry, Grace, Seja, Elizabeth, Berent-Maoz, Beata, Shintaku, I. Peter, Le, Dung Thi, Pardoll, Drew M., Diaz, Luis A., Tumeh, Paul C., Graeber, Thomas G., Lo, Roger S., Comin-Anduix, Begoña, Ribas, Antoni
Publicado no Cancer Discov (2016)

Clinical Features and Outcomes of Immune Checkpoint Inhibitor–Associated AKI: A Multicenter Study

Por Cortazar, Frank B., Kibbelaar, Zoe A., Glezerman, Ilya G., Abudayyeh, Ala, Mamlouk, Omar, Motwani, Shveta S., Murakami, Naoka, Herrmann, Sandra M., Manohar, Sandhya, Shirali, Anushree C., Kitchlu, Abhijat, Shirazian, Shayan, Assal, Amer, Vijayan, Anitha, Renaghan, Amanda DeMauro, Ortiz-Melo, David I., Rangarajan, Sunil, Malik, A. Bilal, Hogan, Jonathan J., Dinh, Alex R., Shin, Daniel Sanghoon, Marrone, Kristen A., Mithani, Zain, Johnson, Douglas B., Hosseini, Afrooz, Uprety, Deekchha, Sharma, Shreyak, Gupta, Shruti, Reynolds, Kerry L., Sise, Meghan E., Leaf, David E.
Publicado no J Am Soc Nephrol (2020)

Genetic mechanisms of immune evasion in colorectal cancer

Por Grasso, Catherine S., Giannakis, Marios, Wells, Daniel K., Hamada, Tsuyoshi, Mu, Xinmeng Jasmine, Quist, Michael, Nowak, Jonathan A., Nishihara, Reiko, Qian, Zhi Rong, Inamura, Kentaro, Morikawa, Teppei, Nosho, Katsuhiko, Abril-Rodriguez, Gabriel, Connolly, Charles, Escuin-Ordinas, Helena, Geybels, Milan S., Grady, William M., Hsu, Li, Hu-Lieskovan, Siwen, Huyghe, Jeroen R., Kim, Yeon Joo, Krystofinski, Paige, Leisersen, Mark D.M., Montoya, Dennis J., Nadel, Brian B., Pellegrini, Matteo, Pritchard, Colin C., Puig-Saus, Cristina, Quist, Elleanor H., Raphael, Ben J., Salipante, Stephen J., Shin, Daniel Sanghoon, Shinbrot, Eve, Shirts, Brian, Shukla, Sachet, Stanford, Janet L., Sun, Wei, Tsoi, Jennifer, Upfill-Brown, Alexander, Wheeler, David A., Wu, Catherine J., Yu, Ming, Zaidi, Syed H., Zaretsky, Jesse M., Gabriel, Stacey B., Lander, Eric S., Garraway, Levi A., Hudson, Thomas J., Fuchs, Charles S., Ribas, Antoni, Ogino, Shuji, Peters, Ulrike
Publicado no Cancer Discov (2018)