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Functional roles of the A335 and G338 residues of the proton-coupled folate transporter (PCFT-SLC46A1) mutated in hereditary folate malabsorption

The proton-coupled folate transporter (PCFT-SLC46A1) mediates intestinal folate absorption and folate transport across the choroid plexus, processes defective in hereditary folate malabsorption (HFM). This paper characterizes the functional defect, and the roles of two mutated PCFT residues, associa...

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Detalhes bibliográficos
Main Authors: Shin, Daniel Sanghoon, Zhao, Rongbao, Fiser, Andras, Goldman, David I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469714/
https://ncbi.nlm.nih.gov/pubmed/22843796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00171.2012
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