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Functional roles of the A335 and G338 residues of the proton-coupled folate transporter (PCFT-SLC46A1) mutated in hereditary folate malabsorption

The proton-coupled folate transporter (PCFT-SLC46A1) mediates intestinal folate absorption and folate transport across the choroid plexus, processes defective in hereditary folate malabsorption (HFM). This paper characterizes the functional defect, and the roles of two mutated PCFT residues, associa...

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Hlavní autoři: Shin, Daniel Sanghoon, Zhao, Rongbao, Fiser, Andras, Goldman, David I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469714/
https://ncbi.nlm.nih.gov/pubmed/22843796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00171.2012
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