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Role of the fourth transmembrane domain in proton-coupled folate transporter function as assessed by the substituted cysteine accessibility method

The proton-coupled folate transporter (PCFT, SLC46A1) mediates folate transport across the apical brush-border membrane of the proximal small intestine and the basolateral membrane of choroid plexus ependymal cells. Two loss-of-function mutations in PCFT, which are the basis for hereditary folate ma...

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Autors principals: Shin, Daniel Sanghoon, Zhao, Rongbao, Fiser, Andras, Goldman, I. David
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680650/
https://ncbi.nlm.nih.gov/pubmed/23552283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00353.2012
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