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Membrane topological analysis of the proton-coupled folate transporter (PCFT-SLC46A1) by the substituted cysteine accessibility method

The proton-coupled folate transporter (PCFT) mediates intestinal folate absorption. Loss-of-function mutations in this gene are the molecular basis for the autosomal recessive disorder, hereditary folate malabsorption. In this study, the substituted cysteine accessibility method was utilized to loca...

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Main Authors: Zhao, Rongbao, Unal, Ersin Selcuk, Shin, Daniel Sanghoon, Goldman, I. David
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866095/
https://ncbi.nlm.nih.gov/pubmed/20225891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9021439
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