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Role of the glutamate 185 residue in proton translocation mediated by the proton-coupled folate transporter SLC46A1
The proton-coupled folate transporter (PCFT) SLC46A1 mediates uphill folate transport into enterocytes in proximal small intestine coupled to the inwardly directed proton gradient. Hereditary folate malabsorption is due to loss-of-function mutations in the PCFT gene. This study addresses the functio...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711648/ https://ncbi.nlm.nih.gov/pubmed/19403800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00096.2009 |
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