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Substituted-cysteine accessibility and cross-linking identify an exofacial cleft in the 7th and 8th helices of the proton-coupled folate transporter (SLC46A1)

The proton-coupled folate transporter (PCFT-SLC46A1) is required for folate transport across the apical membrane of the small intestine and across the choroid plexus. This study focuses on the structure/function of the 7th transmembrane domain (TMD), and its relationship to the 8th TMD as assessed b...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Aluri, Srinivas, Zhao, Rongbao, Fiser, Andras, Goldman, I. David
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415652/
https://ncbi.nlm.nih.gov/pubmed/29167151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00215.2017
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