PD-1 blockade expands intratumoral T memory cells

Tumor responses to PD-1 blockade therapy are mediated by T cells, which we characterized in 102 tumor biopsies obtained from 53 patients treated with pembrolizumab, an antibody to PD-1. Biopsies were dissociated and single cell infiltrates were analyzed by multicolor flow cytometry using two computa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Ribas, Antoni, Shin, Daniel Sanghoon, Zaretsky, Jesse, Frederiksen, Juliet, Cornish, Andrew, Avramis, Earl, Seja, Elizabeth, Kivork, Christine, Siebert, Janet, Kaplan-Lefko, Paula, Wang, Xiaoyan, Chmielowski, Bartosz, Glaspy, John A., Tumeh, Paul C., Chodon, Thinle, Pe’er, Dana, Comin-Anduix, Begoña
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775381/
https://ncbi.nlm.nih.gov/pubmed/26787823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0210
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados