Natural Killer T Cells in Advanced Melanoma Patients Treated with Tremelimumab

A significant barrier to effective immune clearance of cancer is loss of antitumor cytotoxic T cell activity. Antibodies to block pro-apoptotic/downmodulatory signals to T cells are currently being tested. Because invariant natural killer T cells (iNKT) can regulate the balance of Th1/Th2 cellular i...

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Main Authors: Ibarrondo, F. Javier, Yang, Otto O., Chodon, Thinle, Avramis, Earl, Lee, Yohan, Sazegar, Hooman, Jalil, Jason, Chmielowski, Bartosz, Koya, Richard C., Schmid, Ingrid, Gomez-Navarro, Jesus, Jamieson, Beth D., Ribas, Antoni, Comin-Anduix, Begoña
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805549/
https://ncbi.nlm.nih.gov/pubmed/24167550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076829
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