Repurposing metformin for cancer treatment: current clinical studies

In recent years, several studies have presented evidence suggesting a potential role for metformin in anti-cancer therapy. Preclinical studies have demonstrated several anticancer molecular mechanisms of metformin including mTOR inhibition, cytotoxic effects, and immunomodulation. Epidemiologic data...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chae, Young Kwang, Arya, Ayush, Malecek, Mary-Kate, Shin, Daniel Sanghoon, Carneiro, Benedito, Chandra, Sunandana, Kaplan, Jason, Kalyan, Aparna, Altman, Jessica K., Platanias, Leonidas, Giles, Francis
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130043/
https://ncbi.nlm.nih.gov/pubmed/27004404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8194
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