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Targeting mTOR signaling pathways and related negative feedback loops for the treatment of acute myeloid leukemia
An accumulating understanding of the complex pathogenesis of acute myeloid leukemia (AML) continues to lead to promising therapeutic approaches. Among the key aberrant intracellular signaling pathways involved in AML, the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (PI3K/AKT/mTOR...
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| Опубликовано в: : | Cancer Biol Ther |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622839/ https://ncbi.nlm.nih.gov/pubmed/25801978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1026510 |
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