Targeting mTOR signaling pathways and related negative feedback loops for the treatment of acute myeloid leukemia

An accumulating understanding of the complex pathogenesis of acute myeloid leukemia (AML) continues to lead to promising therapeutic approaches. Among the key aberrant intracellular signaling pathways involved in AML, the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (PI3K/AKT/mTOR...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Biol Ther
Main Authors: Carneiro, Benedito A, Kaplan, Jason B, Altman, Jessica K, Giles, Francis J, Platanias, Leonidas C
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622839/
https://ncbi.nlm.nih.gov/pubmed/25801978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1026510
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