Newly Identified Antibacterial Compounds Are Topoisomerase Poisons in African Trypanosomes

מאת Tang, Sonya C., Shapiro, Theresa A.
יצא לאור 2010

Potent Antitrypanosomal Activities of Heat Shock Protein 90 Inhibitors In Vitro and In Vivo

מאת Meyer, Kirsten J., Shapiro, Theresa A.
יצא לאור 2013

Antitrypanosomal Activity of Fluoroquinolones

מאת Nenortas, Elizabeth, Burri, Christian, Shapiro, Theresa A.
יצא לאור 1999

Model System Identifies Kinetic Driver of Hsp90 Inhibitor Activity against African Trypanosomes and Plasmodium falciparum

מאת Meyer, Kirsten J., Caton, Emily, Shapiro, Theresa A.
הוצא לאור ב Antimicrob Agents Chemother (2018)

Antitrypanosomal Activities of Fluoroquinolones with Pyrrolidinyl Substitutions

מאת Nenortas, Elizabeth, Kulikowicz, Tomasz, Burri, Christian, Shapiro, Theresa A.
יצא לאור 2003

Targeting the gyrase of Plasmodium falciparum with topoisomerase poisons

מאת Tang Girdwood, Sonya C., Nenortas, Elizabeth, Shapiro, Theresa A.
הוצא לאור ב Biochem Pharmacol (2015)

Optimal kinetic exposures for classic and candidate antitrypanosomals

מאת Meyer, Kirsten J, Meyers, David J, Shapiro, Theresa A
הוצא לאור ב J Antimicrob Chemother (2019)

Hollow Fiber Methodology for Pharmacokinetic/Pharmacodynamic Studies of Antimalarial Compounds

מאת Caton, Emily, Nenortas, Elizabeth, Bakshi, Rahul P., Shapiro, Theresa A.
הוצא לאור ב Curr Protoc Chem Biol (2016)

Kinetic Driver of Antibacterial Drugs against Plasmodium falciparum and Implications for Clinical Dosing

מאת Caton, Emily, Nenortas, Elizabeth, Bakshi, Rahul P., Shapiro, Theresa A.
הוצא לאור ב Antimicrob Agents Chemother (2019)

Activity of Indenoisoquinolines against African Trypanosomes

מאת Bakshi, Rahul P., Sang, Dongpei, Morrell, Andrew, Cushman, Mark, Shapiro, Theresa A.
יצא לאור 2009

An unusual type IB topoisomerase from African trypanosomes

מאת Bodley, Annette L., Chakraborty, Asit K., Xie, Suji, Burri, Christian, Shapiro, Theresa A.
יצא לאור 2003

Antimalarial Preclinical Drug Development: A Single Oral Dose of A 5-Carbon-linked Trioxane Dimer Plus Mefloquine Cures Malaria-Infected Mice

מאת Moon, Deuk Kyu, Singhal, Vandana, Kumar, Nirbhay, Shapiro, Theresa A., Posner, Gary H.
יצא לאור 2009

Phase I/II Evaluation of the Prophylactic Antimalarial Activity of Pafuramidine in Healthy Volunteers Challenged with Plasmodium falciparum Sporozoites

מאת Nyunt, Myaing M., Hendrix, Craig W., Bakshi, Rahul P, Kumar, Nirbhay, Shapiro, Theresa A.
יצא לאור 2009

Model System to Define Pharmacokinetic Requirements for Antimalarial Drug Efficacy

מאת Bakshi, Rahul P., Nenortas, Elizabeth, Tripathi, Abhai K., Sullivan, David J., Shapiro, Theresa A.
יצא לאור 2013

Semi-quantitative measurement of the antimalarial lumefantrine from untreated dried blood spots using LC-MS/MS

מאת Ippolito, Matthew M., Huang, Liusheng, Siame, Mwiche, Thuma, Philip, Shapiro, Theresa A., Aweeka, Francesca T.
הוצא לאור ב J Pharm Biomed Anal (2018)

Activity of Aromathecins against African Trypanosomes

מאת Nenortas, Nathaniel P., Cinelli, Maris A., Morrell, Andrew E., Cushman, Mark, Shapiro, Theresa A.
הוצא לאור ב Antimicrob Agents Chemother (2018)

Evidence of Microbiome–Drug Interaction between the Antimalarial Lumefantrine and Gut Microbiota in Mice

מאת Ippolito, Matthew M., Denny, Joshua E., Nenortas, Elizabeth, Shapiro, Theresa A., Schmidt, Nathan W.
הוצא לאור ב Am J Trop Med Hyg (2020)

Malaria-Infected Mice Are Cured by a Single Low Dose of a New Silylamide Trioxane Plus Mefloquine

מאת Woodard, Lauren E., Mott, Bryan T., Singhal, Vandana, Kumar, Nirbhay, Shapiro, Theresa A., Posner, Gary H.
יצא לאור 2009

Malaria-Infected Mice Live Until At Least Day 30 After A New Monomeric Trioxane Combined with Mefloquine Are Administered Together In A Single Low Oral Dose

מאת Woodard, Lauren E., Chang, Wonsuk, Chen, Xiaochun, Liu, Jun O., Shapiro, Theresa A., Posner, Gary H.
יצא לאור 2009

Membrane active chelators as novel anti-African trypanosome and anti-malarial drugs

מאת Grab, Dennis J., Nenortas, Elizabeth, Bakshi, Rahul, Nikolskaia, Olga V., Friedman, Jonathan E., Shapiro, Theresa A.
יצא לאור 2013