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Model System Identifies Kinetic Driver of Hsp90 Inhibitor Activity against African Trypanosomes and Plasmodium falciparum
Hsp90 inhibitors, well studied in the laboratory and clinic for antitumor indications, have promising activity against protozoan pathogens, including Trypanosoma brucei which causes African sleeping sickness, and the malaria parasite, Plasmodium falciparum. To progress these experimental drugs towar...
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| 發表在: | Antimicrob Agents Chemother |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6105818/ https://ncbi.nlm.nih.gov/pubmed/29866861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00056-18 |
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