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Structure of the ATP-binding domain of Plasmodium falciparum Hsp90

Hsp90 is an important cellular chaperone and attractive target for therapeutics against both cancer and infectious organisms. The Hsp90 protein from the parasite Plasmodium falciparum, the causative agent of malaria, is critical for this organism’s survival; the anti-Hsp90 drug geldanamycin is toxic...

詳細記述

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書誌詳細
主要な著者: Corbett, Kevin D., Berger, James M.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927708/
https://ncbi.nlm.nih.gov/pubmed/20635416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22799
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