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Structure of the ATP-binding domain of Plasmodium falciparum Hsp90

Hsp90 is an important cellular chaperone and attractive target for therapeutics against both cancer and infectious organisms. The Hsp90 protein from the parasite Plasmodium falciparum, the causative agent of malaria, is critical for this organism’s survival; the anti-Hsp90 drug geldanamycin is toxic...

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Detalhes bibliográficos
Main Authors: Corbett, Kevin D., Berger, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927708/
https://ncbi.nlm.nih.gov/pubmed/20635416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22799
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