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Crystallographic structure of the tetratricopeptide repeat domain of Plasmodium falciparum FKBP35 and its molecular interaction with Hsp90 C-terminal pentapeptide

Plasmodium falciparum FK506-binding protein 35 (PfFKBP35) that binds to FK506 contains a conserved tetratricopeptide repeat (TPR) domain. Several known TPR domains such as Hop, PPP5, CHIP, and FKBP52 are structurally conserved and are able to interact with molecular chaperones such as Hsp70/Hsp90. H...

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Detalhes bibliográficos
Main Authors: Alag, Reema, Bharatham, Nagakumar, Dong, Aiping, Hills, Tanya, Harikishore, Amaravadhi, Widjaja, Anissa Anindya, Shochat, Susana Geifman, Hui, Raymond, Yoon, Ho Sup
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786975/
https://ncbi.nlm.nih.gov/pubmed/19691130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.226
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