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NMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodium vivax FKBP35

The emergence of drug-resistant malaria parasites is the major threat to effective malaria control, prompting a search for novel compounds with mechanisms of action that are different from the traditionally used drugs. The immunosuppressive drug FK506 shows an antimalarial activity. The mechanism of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alag, Reema, Qureshi, Insaf A, Bharatham, Nagakumar, Shin, Joon, Lescar, Julien, Yoon, Ho Sup
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley Subscription Services, Inc., A Wiley Company 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923510/
https://ncbi.nlm.nih.gov/pubmed/20572013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.438
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