Adamantyl Derivative As a Potent Inhibitor of Plasmodium FK506 Binding Protein 35

[Image: see text] FKBP35, FK506 binding protein family member, in Plasmodium species displays a canonical peptidyl-prolyl isomerase (PPIase) activity and is intricately involved in the protein folding process. Inhibition of PfFKBP35 by FK506 or its analogues were shown to interfere with the in vitro...

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Hlavní autoři: Harikishore, Amaravadhi, Leow, Min Li, Niang, Makhtar, Rajan, Sreekanth, Pasunooti, Kalyan Kumar, Preiser, Peter Rainer, Liu, Xuewei, Yoon, Ho Sup
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2013
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027365/
https://ncbi.nlm.nih.gov/pubmed/24900611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400306r
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