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Crystal structure of the FK506 binding domain of human FKBP25 in complex with FK506
Human FKBP25 (hFKBP25) is a nuclear immunophilin and interacts with several nuclear proteins, hence involving in many nuclear events. Similar to other FKBPs, FK506 binding domain (FKBD) of hFKBP25 also binds to immunosuppressive drugs such as rapamycin and FK506, albeit with a lower affinity for the...
Tallennettuna:
| Julkaisussa: | Protein Sci |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
John Wiley and Sons Inc.
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4941220/ https://ncbi.nlm.nih.gov/pubmed/26749369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2875 |
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