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Crystal structure of the FK506 binding domain of human FKBP25 in complex with FK506

Human FKBP25 (hFKBP25) is a nuclear immunophilin and interacts with several nuclear proteins, hence involving in many nuclear events. Similar to other FKBPs, FK506 binding domain (FKBD) of hFKBP25 also binds to immunosuppressive drugs such as rapamycin and FK506, albeit with a lower affinity for the...

詳細記述

保存先:
書誌詳細
出版年:Protein Sci
主要な著者: Prakash, Ajit, Rajan, Sreekanth, Yoon, Ho Sup
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941220/
https://ncbi.nlm.nih.gov/pubmed/26749369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2875
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