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Structure of the ATP-binding domain of Plasmodium falciparum Hsp90
Hsp90 is an important cellular chaperone and attractive target for therapeutics against both cancer and infectious organisms. The Hsp90 protein from the parasite Plasmodium falciparum, the causative agent of malaria, is critical for this organism’s survival; the anti-Hsp90 drug geldanamycin is toxic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927708/ https://ncbi.nlm.nih.gov/pubmed/20635416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22799 |
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