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Newly Identified Antibacterial Compounds Are Topoisomerase Poisons in African Trypanosomes
Human African trypanosomiasis, caused by the Trypanosoma brucei protozoan parasite, is fatal when left untreated. Current therapies are antiquated, and there is a need for new pharmacologic agents against T. brucei targets that have no human ortholog. Trypanosomes have a single mitochondrion with a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812133/ https://ncbi.nlm.nih.gov/pubmed/20008775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01025-09 |
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