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Targeting the gyrase of Plasmodium falciparum with topoisomerase poisons
Drug-resistant malaria poses a major public health problem throughout the world and the need for new antimalarial drugs is growing. The apicoplast, a chloroplast-like organelle essential for malaria parasite survival and with no counterpart in humans, offers an attractive target for selectively toxi...
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| Publié dans: | Biochem Pharmacol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4449814/ https://ncbi.nlm.nih.gov/pubmed/25881748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.03.018 |
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