Accumulation and Intracellular Distribution of Antitrypanosomal Diamidine Compounds DB75 and DB820 in African Trypanosomes

The aromatic diamidine pentamidine has long been used to treat early-stage human African trypanosomiasis (HAT). Two analogs of pentamidine, DB75 and DB820, have been shown to be more potent and less toxic than pentamidine in murine models of trypanosomiasis. The diphenyl furan diamidine, DB75, is th...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Mathis, Amanda M., Holman, Jacqueline L., Sturk, Lisa M., Ismail, Mohamed A., Boykin, David W., Tidwell, Richard R., Hall, James Edwin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2006
Предметы:
Mechanisms of Action: Physiological Effects
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479144/
https://ncbi.nlm.nih.gov/pubmed/16723581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00192-06
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы