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The diamidine DB75 targets the nucleus of Plasmodium falciparum
BACKGROUND: DB289, [2,5-bis(4-amidinophenyl)furan bis-O-methylamidoxime], is a broad spectrum anti-parasitic compound which has been shown to be effective against malaria in recent clinical trials. DB75, [2,5-bis(4-amidinophenyl)furan], is the active metabolite of this drug. The objective of this st...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2689252/ https://ncbi.nlm.nih.gov/pubmed/19442305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-8-104 |
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