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DB75, a Novel Trypanocidal Agent, Disrupts Mitochondrial Function in Saccharomyces cerevisiae

The aromatic diamidines represent a class of compounds with broad-spectrum antimicrobial activity; however, their development is hindered by a lack of understanding of their mechanism of antimicrobial action. DB75 [2,5-bis(4-amidinophenyl)furan] is a trypanocidal aromatic diamidine that was original...

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Autors principals: Lanteri, Charlotte A., Trumpower, Bernard L., Tidwell, Richard R., Meshnick, Steven R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC521894/
https://ncbi.nlm.nih.gov/pubmed/15388460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3968-3974.2004
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