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Semi-quantitative measurement of the antimalarial lumefantrine from untreated dried blood spots using LC-MS/MS

Study of the clinical effects of combination therapy for malaria is aided by the ability to measure concentrations of individual partner drugs. Existing methods for measurement of the antimalarial drug lumefantrine (LF) in dried blood spots (DBS) on filter paper rely on chemical pretreatment of the...

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Detalhes bibliográficos
Publicado no:J Pharm Biomed Anal
Main Authors: Ippolito, Matthew M., Huang, Liusheng, Siame, Mwiche, Thuma, Philip, Shapiro, Theresa A., Aweeka, Francesca T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949273/
https://ncbi.nlm.nih.gov/pubmed/29655094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2018.04.002
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