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Determination of the antimalarial drug piperaquine in small volume pediatric plasma samples by LC–MS/MS
AIM: Determination of piperaquine (PQ) in pediatric plasma requires a method with a small sample volume. RESULTS: We report a sensitive LC–MS/MS method for quantitation of PQ with only 25 µI human plasma. Using a deuterated internal standard (PQ-d(6)), an analytical PFP column, APCI(+) as the ion so...
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| Pubblicato in: | Bioanalysis |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4321809/ https://ncbi.nlm.nih.gov/pubmed/25529877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio.14.254 |
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