Determination of piperaquine concentration in human plasma and the correlation of capillary versus venous plasma concentrations

BACKGROUND: A considerable challenge in quantification of the antimalarial piperaquine in plasma is carryover of analyte signal between assays. Current intensive pharmacokinetic studies often rely on the merging of venous and capillary sampling. Drug levels in capillary plasma may be different from...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mwebaza, Norah, Cheah, Vincent, Forsman, Camilla, Kajubi, Richard, Marzan, Florence, Wallender, Erika, Dorsey, Grant, Rosenthal, Philip J., Aweeka, Francesca, Huang, Liusheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259774/
https://ncbi.nlm.nih.gov/pubmed/32470030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233893
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