Determination of piperaquine concentration in human plasma and the correlation of capillary versus venous plasma concentrations

BACKGROUND: A considerable challenge in quantification of the antimalarial piperaquine in plasma is carryover of analyte signal between assays. Current intensive pharmacokinetic studies often rely on the merging of venous and capillary sampling. Drug levels in capillary plasma may be different from...

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Publicado en:PLoS One
Autores principales: Mwebaza, Norah, Cheah, Vincent, Forsman, Camilla, Kajubi, Richard, Marzan, Florence, Wallender, Erika, Dorsey, Grant, Rosenthal, Philip J., Aweeka, Francesca, Huang, Liusheng
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259774/
https://ncbi.nlm.nih.gov/pubmed/32470030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233893
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