Antiretroviral therapy with efavirenz accentuates pregnancy-associated reduction of dihydroartemisinin-piperaquine exposure during malaria chemoprevention

Dihydroartemisinin (DHA)-piperaquine is promising for malaria chemoprevention in pregnancy. We assessed impacts of pregnancy and efavirenz-based antiretroviral therapy on exposure to DHA and piperaquine in pregnant Ugandan women. Intensive sampling was performed at 28 weeks gestation in 31 HIV-uninf...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Clin Pharmacol Ther
Main Authors: Kajubi, Richard, Huang, Liusheng, Jagannathan, Prasanna, Chamankhah, Nona, Were, Moses, Ruel, Theodore., Koss, Catherine A., Kakuru, Abel, Mwebaza, Norah, Kamya, Moses, Havlir, Diane, Dorsey, Grant, Rosenthal, Philip J., Aweeka, Francesca T.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546920/
https://ncbi.nlm.nih.gov/pubmed/28187497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.664
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