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Model System to Define Pharmacokinetic Requirements for Antimalarial Drug Efficacy

Malaria presents a tremendous public health burden and new therapies are needed. Massive compound libraries screened against Plasmodium falciparum have yielded thousands of lead compounds, resulting in an acute need for rational criteria to select the best candidates for development. We reasoned tha...

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Detalhes bibliográficos
Main Authors: Bakshi, Rahul P., Nenortas, Elizabeth, Tripathi, Abhai K., Sullivan, David J., Shapiro, Theresa A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845824/
https://ncbi.nlm.nih.gov/pubmed/24089407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006684
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