Newly Identified Antibacterial Compounds Are Topoisomerase Poisons in African Trypanosomes

gan Tang, Sonya C., Shapiro, Theresa A.
Cyhoeddwyd 2010

Potent Antitrypanosomal Activities of Heat Shock Protein 90 Inhibitors In Vitro and In Vivo

gan Meyer, Kirsten J., Shapiro, Theresa A.
Cyhoeddwyd 2013

Antitrypanosomal Activity of Fluoroquinolones

gan Nenortas, Elizabeth, Burri, Christian, Shapiro, Theresa A.
Cyhoeddwyd 1999

Model System Identifies Kinetic Driver of Hsp90 Inhibitor Activity against African Trypanosomes and Plasmodium falciparum

gan Meyer, Kirsten J., Caton, Emily, Shapiro, Theresa A.
Cyhoeddwyd yn Antimicrob Agents Chemother (2018)

Antitrypanosomal Activities of Fluoroquinolones with Pyrrolidinyl Substitutions

gan Nenortas, Elizabeth, Kulikowicz, Tomasz, Burri, Christian, Shapiro, Theresa A.
Cyhoeddwyd 2003

Targeting the gyrase of Plasmodium falciparum with topoisomerase poisons

gan Tang Girdwood, Sonya C., Nenortas, Elizabeth, Shapiro, Theresa A.
Cyhoeddwyd yn Biochem Pharmacol (2015)

Optimal kinetic exposures for classic and candidate antitrypanosomals

gan Meyer, Kirsten J, Meyers, David J, Shapiro, Theresa A
Cyhoeddwyd yn J Antimicrob Chemother (2019)

Hollow Fiber Methodology for Pharmacokinetic/Pharmacodynamic Studies of Antimalarial Compounds

gan Caton, Emily, Nenortas, Elizabeth, Bakshi, Rahul P., Shapiro, Theresa A.
Cyhoeddwyd yn Curr Protoc Chem Biol (2016)

Kinetic Driver of Antibacterial Drugs against Plasmodium falciparum and Implications for Clinical Dosing

gan Caton, Emily, Nenortas, Elizabeth, Bakshi, Rahul P., Shapiro, Theresa A.
Cyhoeddwyd yn Antimicrob Agents Chemother (2019)

Activity of Indenoisoquinolines against African Trypanosomes

gan Bakshi, Rahul P., Sang, Dongpei, Morrell, Andrew, Cushman, Mark, Shapiro, Theresa A.
Cyhoeddwyd 2009

An unusual type IB topoisomerase from African trypanosomes

gan Bodley, Annette L., Chakraborty, Asit K., Xie, Suji, Burri, Christian, Shapiro, Theresa A.
Cyhoeddwyd 2003

Antimalarial Preclinical Drug Development: A Single Oral Dose of A 5-Carbon-linked Trioxane Dimer Plus Mefloquine Cures Malaria-Infected Mice

gan Moon, Deuk Kyu, Singhal, Vandana, Kumar, Nirbhay, Shapiro, Theresa A., Posner, Gary H.
Cyhoeddwyd 2009

Phase I/II Evaluation of the Prophylactic Antimalarial Activity of Pafuramidine in Healthy Volunteers Challenged with Plasmodium falciparum Sporozoites

gan Nyunt, Myaing M., Hendrix, Craig W., Bakshi, Rahul P, Kumar, Nirbhay, Shapiro, Theresa A.
Cyhoeddwyd 2009

Model System to Define Pharmacokinetic Requirements for Antimalarial Drug Efficacy

gan Bakshi, Rahul P., Nenortas, Elizabeth, Tripathi, Abhai K., Sullivan, David J., Shapiro, Theresa A.
Cyhoeddwyd 2013

Semi-quantitative measurement of the antimalarial lumefantrine from untreated dried blood spots using LC-MS/MS

gan Ippolito, Matthew M., Huang, Liusheng, Siame, Mwiche, Thuma, Philip, Shapiro, Theresa A., Aweeka, Francesca T.
Cyhoeddwyd yn J Pharm Biomed Anal (2018)

Activity of Aromathecins against African Trypanosomes

gan Nenortas, Nathaniel P., Cinelli, Maris A., Morrell, Andrew E., Cushman, Mark, Shapiro, Theresa A.
Cyhoeddwyd yn Antimicrob Agents Chemother (2018)

Evidence of Microbiome–Drug Interaction between the Antimalarial Lumefantrine and Gut Microbiota in Mice

gan Ippolito, Matthew M., Denny, Joshua E., Nenortas, Elizabeth, Shapiro, Theresa A., Schmidt, Nathan W.
Cyhoeddwyd yn Am J Trop Med Hyg (2020)

Malaria-Infected Mice Are Cured by a Single Low Dose of a New Silylamide Trioxane Plus Mefloquine

gan Woodard, Lauren E., Mott, Bryan T., Singhal, Vandana, Kumar, Nirbhay, Shapiro, Theresa A., Posner, Gary H.
Cyhoeddwyd 2009

Malaria-Infected Mice Live Until At Least Day 30 After A New Monomeric Trioxane Combined with Mefloquine Are Administered Together In A Single Low Oral Dose

gan Woodard, Lauren E., Chang, Wonsuk, Chen, Xiaochun, Liu, Jun O., Shapiro, Theresa A., Posner, Gary H.
Cyhoeddwyd 2009

Membrane active chelators as novel anti-African trypanosome and anti-malarial drugs

gan Grab, Dennis J., Nenortas, Elizabeth, Bakshi, Rahul, Nikolskaia, Olga V., Friedman, Jonathan E., Shapiro, Theresa A.
Cyhoeddwyd 2013