Newly Identified Antibacterial Compounds Are Topoisomerase Poisons in African Trypanosomes

per Tang, Sonya C., Shapiro, Theresa A.
Publicat 2010

Potent Antitrypanosomal Activities of Heat Shock Protein 90 Inhibitors In Vitro and In Vivo

per Meyer, Kirsten J., Shapiro, Theresa A.
Publicat 2013

Antitrypanosomal Activity of Fluoroquinolones

per Nenortas, Elizabeth, Burri, Christian, Shapiro, Theresa A.
Publicat 1999

Model System Identifies Kinetic Driver of Hsp90 Inhibitor Activity against African Trypanosomes and Plasmodium falciparum

per Meyer, Kirsten J., Caton, Emily, Shapiro, Theresa A.
Publicat a Antimicrob Agents Chemother (2018)

Antitrypanosomal Activities of Fluoroquinolones with Pyrrolidinyl Substitutions

per Nenortas, Elizabeth, Kulikowicz, Tomasz, Burri, Christian, Shapiro, Theresa A.
Publicat 2003

Targeting the gyrase of Plasmodium falciparum with topoisomerase poisons

per Tang Girdwood, Sonya C., Nenortas, Elizabeth, Shapiro, Theresa A.
Publicat a Biochem Pharmacol (2015)

Optimal kinetic exposures for classic and candidate antitrypanosomals

per Meyer, Kirsten J, Meyers, David J, Shapiro, Theresa A
Publicat a J Antimicrob Chemother (2019)

Hollow Fiber Methodology for Pharmacokinetic/Pharmacodynamic Studies of Antimalarial Compounds

per Caton, Emily, Nenortas, Elizabeth, Bakshi, Rahul P., Shapiro, Theresa A.
Publicat a Curr Protoc Chem Biol (2016)

Kinetic Driver of Antibacterial Drugs against Plasmodium falciparum and Implications for Clinical Dosing

per Caton, Emily, Nenortas, Elizabeth, Bakshi, Rahul P., Shapiro, Theresa A.
Publicat a Antimicrob Agents Chemother (2019)

Activity of Indenoisoquinolines against African Trypanosomes

per Bakshi, Rahul P., Sang, Dongpei, Morrell, Andrew, Cushman, Mark, Shapiro, Theresa A.
Publicat 2009

An unusual type IB topoisomerase from African trypanosomes

per Bodley, Annette L., Chakraborty, Asit K., Xie, Suji, Burri, Christian, Shapiro, Theresa A.
Publicat 2003

Antimalarial Preclinical Drug Development: A Single Oral Dose of A 5-Carbon-linked Trioxane Dimer Plus Mefloquine Cures Malaria-Infected Mice

per Moon, Deuk Kyu, Singhal, Vandana, Kumar, Nirbhay, Shapiro, Theresa A., Posner, Gary H.
Publicat 2009

Phase I/II Evaluation of the Prophylactic Antimalarial Activity of Pafuramidine in Healthy Volunteers Challenged with Plasmodium falciparum Sporozoites

per Nyunt, Myaing M., Hendrix, Craig W., Bakshi, Rahul P, Kumar, Nirbhay, Shapiro, Theresa A.
Publicat 2009

Model System to Define Pharmacokinetic Requirements for Antimalarial Drug Efficacy

per Bakshi, Rahul P., Nenortas, Elizabeth, Tripathi, Abhai K., Sullivan, David J., Shapiro, Theresa A.
Publicat 2013

Semi-quantitative measurement of the antimalarial lumefantrine from untreated dried blood spots using LC-MS/MS

per Ippolito, Matthew M., Huang, Liusheng, Siame, Mwiche, Thuma, Philip, Shapiro, Theresa A., Aweeka, Francesca T.
Publicat a J Pharm Biomed Anal (2018)

Activity of Aromathecins against African Trypanosomes

per Nenortas, Nathaniel P., Cinelli, Maris A., Morrell, Andrew E., Cushman, Mark, Shapiro, Theresa A.
Publicat a Antimicrob Agents Chemother (2018)

Evidence of Microbiome–Drug Interaction between the Antimalarial Lumefantrine and Gut Microbiota in Mice

per Ippolito, Matthew M., Denny, Joshua E., Nenortas, Elizabeth, Shapiro, Theresa A., Schmidt, Nathan W.
Publicat a Am J Trop Med Hyg (2020)

Malaria-Infected Mice Are Cured by a Single Low Dose of a New Silylamide Trioxane Plus Mefloquine

per Woodard, Lauren E., Mott, Bryan T., Singhal, Vandana, Kumar, Nirbhay, Shapiro, Theresa A., Posner, Gary H.
Publicat 2009

Malaria-Infected Mice Live Until At Least Day 30 After A New Monomeric Trioxane Combined with Mefloquine Are Administered Together In A Single Low Oral Dose

per Woodard, Lauren E., Chang, Wonsuk, Chen, Xiaochun, Liu, Jun O., Shapiro, Theresa A., Posner, Gary H.
Publicat 2009

Membrane active chelators as novel anti-African trypanosome and anti-malarial drugs

per Grab, Dennis J., Nenortas, Elizabeth, Bakshi, Rahul, Nikolskaia, Olga V., Friedman, Jonathan E., Shapiro, Theresa A.
Publicat 2013