Understanding Obesity and Endometrial Cancer Risk: Opportunities for Prevention

Por SCHMANDT, Rosemarie E., IGLESIAS, David A., CO, Ngai Na, LU, Karen H.
Publicado no Am J Obstet Gynecol (2011)

Loss of LKB1 in High Grade Endometrial Carcinoma: LKB1 is a Novel Transcriptional Target of p53

Por Co, Ngai Na, Iglesias, David, Celestino, Joseph, Kwan, Suet Y., Mok, Samuel C., Schmandt, Rosemarie, Lu, Karen H.
Publicado no Cancer (2014)

Lean body weight and metformin are insufficient to prevent endometrial hyperplasia in mice harboring inactivating mutations in PTEN

Por IGLESIAS, David A., ZHANG, Qian, CELESTINO, Joseph, SUN, Charlotte C., YATES, Melinda S., SCHMANDT, Rosemarie E., LU, Karen H.
Publicado no Oncology (2016)

Prospective evaluation of the molecular effects of metformin on the endometrium in women with newly diagnosed endometrial cancer: A window of opportunity study

Por Soliman, Pamela T., Zhang, Qian, Broaddus, Russell R., Westin, Shannon N., Iglesias, David, Munsell, Mark F., Schmandt, Rosemarie, Yates, Melinda, Ramondetta, Lois, Lu, Karen H.
Publicado no Gynecol Oncol (2016)

CGRRF1 as a novel biomarker of tissue response to metformin in the context of obesity

Por Zhang, Qian, Schmandt, Rosemarie, Celestino, Joseph, McCampbell, Adrienne, Yates, Melinda S., Urbauer, Diana L., Broaddus, Russell R., Loose, David S., Shipley, Gregory L., Lu, Karen H.
Publicado em 2014

Overexpression of SnoN/SkiL, amplified at the 3q26.2 locus, in ovarian cancers: A role in ovarian pathogenesis

Por Nanjundan, Meera, Cheng, Kwai Wa, Zhang, Fan, Lahad, John, Kuo, Wen-Lin, Schmandt, Rosemarie, Smith-McCune, Karen, Fishman, David, Gray, Joe W., Mills, Gordon B.
Publicado em 2008

Focal Adhesion Kinase Silencing Augments Docetaxel-Mediated Apoptosis in Ovarian Cancer Cells

Por Halder, Jyotsnabaran, Landen, Charles N., Lutgendorf, Susan K., Li, Yang, Jennings, Nicholas B., Fan, Dominic, Nelkin, Gina M., Schmandt, Rosemarie, Schaller, Michael D., Sood, Anil K.
Publicado em 2005

Omental adipose tissue-derived stromal cells promote vascularization and growth of endometrial tumors

Por Klopp, Ann H., Zhang, Yan, Solley, Travis, Amaya-Manzanares, Felipe, Marini, Frank, Andreeff, Michael, Debeb, Bisrat, Woodward, Wendy, Schmandt, Rosemarie, Broaddus, Russell, Lu, Karen, Kolonin, Mikhail G.
Publicado em 2011

Chemopreventive effects of metformin on obesity-associated endometrial proliferation

Por ZHANG, Qian, CELESTINO, Joseph, SCHMANDT, Rosemarie, MCCAMPBELL, Adrienne S., URBAUER, Diana L, MEYER, Larissa A., BURZAWA, Jennifer K., HUANG, Marilyn, YATES, Melinda S., IGLESIAS, David, BROADDUS, Russell R., LU, Karen H.
Publicado em 2013

Estrous cycle modulates ovarian carcinoma growth

Por Armaiz-Pena, Guillermo N., Mangala, Lingegowda S., Spannuth, Whitney A., Lin, Yvonne G., Jennings, Nicholas B., Nick, Alpa M., Langley, Robert R., Schmandt, Rosemarie, Lutgendorf, Susan K., Cole, Steven W., Sood, Anil K.
Publicado em 2009

The search continues: Looking for predictive biomarkers for response to mTOR inhibition in endometrial cancer

Por Meyer, Larissa A., Slomovitz, Brian M., Djordjevic, Bojana, Westin, Shannon N., Iglesias, David A., Munsell, Mark F., Jiang, Yunyun, Schmandt, Rosemarie, Broaddus, Russell R., Coleman, Robert L., Galbincea, John M., Lu, Karen H.
Publicado em 2014

Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1

Por Au Yeung, Chi Lam, Co, Ngai-Na, Tsuruga, Tetsushi, Yeung, Tsz-Lun, Kwan, Suet-Ying, Leung, Cecilia S., Li, Yong, Lu, Edward S., Kwan, Kenny, Wong, Kwong-Kwok, Schmandt, Rosemarie, Lu, Karen H., Mok, Samuel C.
Publicado no Nat Commun (2016)

Another Surprise from Metformin: Novel Mechanism of Action via K-Ras Influences Endometrial Cancer Response to Therapy

Por Iglesias, David A., Yates, Melinda S., van der Hoeven, Dharini, Rodkey, Travis L., Zhang, Qian, Co, Ngai Na, Burzawa, Jennifer, Chigurupati, Sravanthi, Celestino, Joseph, Bowser, Jessica, Broaddus, Russell, Hancock, John F., Schmandt, Rosemarie, Lu, Karen H.
Publicado em 2013

Focal Adhesion Kinase Targeting Using In vivo Short Interfering RNA Delivery in Neutral Liposomes for Ovarian Carcinoma Therapy

Por Halder, Jyotsnabaran, Kamat, Aparna A., Landen, Charles N., Han, Liz Y., Lutgendorf, Susan K., Lin, Yvonne G., Merritt, William M., Jennings, Nicholas B., Chavez-Reyes, Arturo, Coleman, Robert L., Gershenson, David M., Schmandt, Rosemarie, Cole, Steven W., Lopez-Berestein, Gabriel, Sood, Anil K.
Publicado em 2006

Targeting pericytes with a PDGF-B aptamer in human ovarian carcinoma models

Por Lu, Chunhua, Shahzad, Mian M.K., Moreno-Smith, Myrthala, Lin, Yvonne G., Jennings, Nicholas B., Allen, Julie K., Landen, Charles N., Mangala, Lingegowda S., Armaiz-Pena, Guillermo N., Schmandt, Rosemarie, Nick, Alpa M., Stone, Rebecca L., Jaffe, Robert B., Coleman, Robert L., Sood, Anil K.
Publicado em 2010

EphA2 Immunoconjugate as Molecularly Targeted Chemotherapy for Ovarian Carcinoma

Por Lee, Jeong-Won, Han, Hee Dong, Shahzad, Mian M. K., Kim, Seung Wook, Mangala, Lingegowda S., Nick, Alpa M., Lu, Chunhua, Langley, Robert R., Schmandt, Rosemarie, Kim, Hye-Sun, Mao, Shenlan, Gooya, John, Fazenbaker, Christine, Jackson, Dowdy, Tice, David A., Landen, Charles N., Coleman, Robert L., Sood, Anil K.
Publicado em 2009

Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer

Por Merritt, William M., Lin, Yvonne G., Han, Liz Y., Kamat, Aparna A., Spannuth, Whitney A., Schmandt, Rosemarie, Urbauer, Diana, Pennacchio, Len A., Cheng, Jan-Fang, Nick, Alpa M., Deavers, Michael T., Mourad-Zeidan, Alexandra, Wang, Hua, Mueller, Peter, Lenburg, Marc E., Gray, Joe W., Mok, Samuel, Birrer, Michael J., Lopez-Berestein, Gabriel, Coleman, Robert L., Bar-Eli, Menashe, Sood, Anil K.
Publicado em 2008

Therapeutic Targeting of ATP7B in Ovarian Carcinoma

Por Mangala, Lingegowda S., Zuzel, Vesna, Schmandt, Rosemarie, Leshane, Erik S., Halder, Jyotsna B., Armaiz-Pena, Guillermo N., Spannuth, Whitney A., Tanaka, Takemi, Shahzad, Mian M.K., Lin, Yvonne G., Nick, Alpa M., Danes, Christopher G., Lee, Jeong-Won, Jennings, Nicholas B., Vivas-Mejia, Pablo E., Wolf, Judith K., Coleman, Robert L., Siddik, Zahid H., Lopez-Berestein, Gabriel, Lutsenko, Svetlana, Sood, Anil K.
Publicado em 2009

ATP11B mediates platinum resistance in ovarian cancer

Por Moreno-Smith, Myrthala, Halder, J.B., Meltzer, Paul S., Gonda, Tamas A., Mangala, Lingegowda S., Rupaimoole, Rajesha, Lu, Chunhua, Nagaraja, Archana S., Gharpure, Kshipra M., Kang, Yu, Rodriguez-Aguayo, Cristian, Vivas-Mejia, Pablo E., Zand, Behrouz, Schmandt, Rosemarie, Wang, Hua, Langley, Robert R., Jennings, Nicholas B., Ivan, Cristina, Coffin, Jeremy E., Armaiz, Guillermo N., Bottsford-Miller, Justin, Kim, Sang Bae, Halleck, Margaret S., Hendrix, Mary J.C., Bornman, William, Bar-Eli, Menashe, Lee, Ju-Seog, Siddik, Zahid H., Lopez-Berestein, Gabriel, Sood, Anil K.
Publicado em 2013

ATP11B mediates platinum resistance in ovarian cancer

Por Moreno-Smith, Myrthala, Halder, J.B., Meltzer, Paul S., Gonda, Tamas A., Mangala, Lingegowda S., Rupaimoole, Rajesha, Lu, Chunhua, Nagaraja, Archana S., Gharpure, Kshipra M., Kang, Yu, Rodriguez-Aguayo, Cristian, Vivas-Mejia, Pablo E., Zand, Behrouz, Schmandt, Rosemarie, Wang, Hua, Langley, Robert R., Jennings, Nicholas B., Ivan, Cristina, Coffin, Jeremy E., Armaiz, Guillermo N., Bottsford-Miller, Justin, Kim, Sang Bae, Halleck, Margaret S., Hendrix, Mary J.C., Bornman, William, Bar-Eli, Menashe, Lee, Ju-Seog, Siddik, Zahid H., Lopez-Berestein, Gabriel, Sood, Anil K.
Publicado em 2013