Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer

BACKGROUND: We studied Dicer and Drosha, components of the RNA-interference machinery, in ovarian cancer. METHODS: We measured messenger RNA (mRNA) levels of Dicer and Drosha in specimens of invasive epithelial ovarian cancer from 111 patients, using a quantitative reverse-transcriptase–polymerase-c...

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Hlavní autoři: Merritt, William M., Lin, Yvonne G., Han, Liz Y., Kamat, Aparna A., Spannuth, Whitney A., Schmandt, Rosemarie, Urbauer, Diana, Pennacchio, Len A., Cheng, Jan-Fang, Nick, Alpa M., Deavers, Michael T., Mourad-Zeidan, Alexandra, Wang, Hua, Mueller, Peter, Lenburg, Marc E., Gray, Joe W., Mok, Samuel, Birrer, Michael J., Lopez-Berestein, Gabriel, Coleman, Robert L., Bar-Eli, Menashe, Sood, Anil K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710981/
https://ncbi.nlm.nih.gov/pubmed/19092150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0803785
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