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Drosha and Dicer: Slicers cut from the same cloth
DROSHA and its partner DGCR8 form a heterotrimeric complex named Microprocessor, which is essential for microRNA biogenesis. A recent study by Kwon et al. in Cell reveals the structure of a DROSHA construct in complex with the C-terminal region of DGCR8, thereby unveiling the topology and interactio...
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| Izdano u: | Cell Res |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856758/ https://ncbi.nlm.nih.gov/pubmed/27125999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.19 |
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