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CGRRF1 as a novel biomarker of tissue response to metformin in the context of obesity
OBJECTIVE: Obesity-associated hyperestrogenism and hyperinsulinemia contribute significantly to the pathogenesis of endometrial cancer. We recently demonstrated that metformin, a drug long used for treatment of type 2 diabetes, attenuates both insulin- and estrogen-mediated proliferative signaling i...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077340/ https://ncbi.nlm.nih.gov/pubmed/24680596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2013.12.006 |
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