Chemopreventive effects of metformin on obesity-associated endometrial proliferation

OBJECTIVE: Obesity is a significant contributing factor to endometrial cancer risk. We previously demonstrated that estrogen-induced endometrial proliferation is enhanced in the context of hyperinsulinemia and insulin resistance. In this study we investigate whether pharmacologic agents that modulat...

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Autori principali: ZHANG, Qian, CELESTINO, Joseph, SCHMANDT, Rosemarie, MCCAMPBELL, Adrienne S., URBAUER, Diana L, MEYER, Larissa A., BURZAWA, Jennifer K., HUANG, Marilyn, YATES, Melinda S., IGLESIAS, David, BROADDUS, Russell R., LU, Karen H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819145/
https://ncbi.nlm.nih.gov/pubmed/23500454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2013.03.008
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