Another Surprise from Metformin: Novel Mechanism of Action via K-Ras Influences Endometrial Cancer Response to Therapy

Metformin is an oral biguanide commonly used for the treatment of type II diabetes and has recently been demonstrated to possess anti-proliferative properties that can be exploited for the prevention and treatment of a variety of cancers. The mechanisms underlying this effect have not been fully elu...

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Autors principals: Iglesias, David A., Yates, Melinda S., van der Hoeven, Dharini, Rodkey, Travis L., Zhang, Qian, Co, Ngai Na, Burzawa, Jennifer, Chigurupati, Sravanthi, Celestino, Joseph, Bowser, Jessica, Broaddus, Russell, Hancock, John F., Schmandt, Rosemarie, Lu, Karen H.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883498/
https://ncbi.nlm.nih.gov/pubmed/24077915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0439
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