Another Surprise from Metformin: Novel Mechanism of Action via K-Ras Influences Endometrial Cancer Response to Therapy

Metformin is an oral biguanide commonly used for the treatment of type II diabetes and has recently been demonstrated to possess anti-proliferative properties that can be exploited for the prevention and treatment of a variety of cancers. The mechanisms underlying this effect have not been fully elu...

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Hlavní autoři: Iglesias, David A., Yates, Melinda S., van der Hoeven, Dharini, Rodkey, Travis L., Zhang, Qian, Co, Ngai Na, Burzawa, Jennifer, Chigurupati, Sravanthi, Celestino, Joseph, Bowser, Jessica, Broaddus, Russell, Hancock, John F., Schmandt, Rosemarie, Lu, Karen H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883498/
https://ncbi.nlm.nih.gov/pubmed/24077915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0439
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