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Molecular Pathogenesis of Endometrial Cancers in Lynch Syndrome

OBJECTIVE: We hypothesized that Lynch Syndrome (LS)-associated endometrial cancer (EC) develops from morphologically normal endometrium that accumulates molecular changes to progress through a continuum of hyperplasia to carcinoma, similar to sporadic EC. The primary objective of this study was to d...

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Detalhes bibliográficos
Main Authors: Huang, Marilyn, Djordjevic, Bojana, Yates, Melinda S., Urbauer, Diana, Sun, Charlotte, Burzawa, Jennifer, Daniels, Molly, Westin, Shannon N., Broaddus, Russell, Lu, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120439/
https://ncbi.nlm.nih.gov/pubmed/23760948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28152
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