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EphA2 Immunoconjugate as Molecularly Targeted Chemotherapy for Ovarian Carcinoma
BACKGROUND: EphA2 is overexpressed in many types of human cancer but is absent or expressed at low levels in normal epithelial tissues. We investigated whether a novel immunoconjugate containing an anti-EphA2 monoclonal antibody (1C1) linked to a chemotherapeutic agent (monomethyl auristatin phenyla...
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Main Authors: | , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736292/ https://ncbi.nlm.nih.gov/pubmed/19641174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp231 |
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